Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections

Antibodies to repeat-containing antigens in Plasmodium falciparum are exposure-dependent and short-lived in children in natural malaria infections

Protection against Plasmodium falciparum, which is primarily antibody-mediated, requires recurrent exposure to develop. The study of both naturally acquired limited immunity and vaccine induced protection against malaria remains critical for ongoing eradication efforts. Towards this goal, we deploye...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Madhura Raghavan, Katrina L Kalantar, Elias Duarte, Noam Teyssier, Saki Takahashi, Andrew F Kung, Jayant V Rajan, John Rek, Kevin KA Tetteh, Chris Drakeley, Isaac Ssewanyana, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Joseph L DeRisi
Format: Artykuł
Język:English
Wydane: eLife Sciences Publications Ltd 2023-02-01
Seria:eLife
Hasła przedmiotowe:
antibodies
phage display
repeat regions
malaria
antigen profiling
natural immunity
Dostęp online:https://elifesciences.org/articles/81401

Internet

https://elifesciences.org/articles/81401

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