DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4

DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4

Chemoresistance cells have features similar to cancer stem cells. Elimination of these cells is an effective therapeutic strategy to clinically combat chemoresistance non-small cell lung cancer (NSCLC). Here, we demonstrate that Doublecortin-like kinase1 (DCLK1) is the key to developing chemoresista...

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Bibliographic Details
Main Authors: Janani Panneerselvam, Priyanga Mohandoss, Ravi Patel, Hamza Gillan, Michael Li, Kirtana Kumar, DangHuy Nguyen, Nathaniel Weygant, Dongfeng Qu, Kamille Pitts, Stanley Lightfoot, Chinthalapally Rao, Courtney Houchen, Michael Bronze, Parthasarathy Chandrakesan
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
cisplatin resistance
non-small cell lung cancer
Chemoresistance
DCLK1
ABC transporters
ABCD4
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300759

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http://www.sciencedirect.com/science/article/pii/S2372770520300759

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