iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation

iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation

Introduction: Despite the high morbidity and mortality of heart failure with preserved fraction (HFpEF), there are currently no effective therapies for this condition. Moreover, the pathophysiological basis of HFpEF remains poorly understood. Objective: The aim of the present study was to investigat...

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Bibliographic Details
Main Authors: Yongzheng Guo, Junjie Wen, An He, Can Qu, Yuce Peng, Suxin Luo, Xiaowen Wang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Advanced Research
Subjects:
HFpEF
iNOS
Akt S-nitrosylation
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222000649

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http://www.sciencedirect.com/science/article/pii/S2090123222000649

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