Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways [version 1; referees: 3 approved]

Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states. Although in the acute stages it is necessary for protective reflexes and wound healing, infla...

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Bibliographic Details
Main Authors: Zhonghui Guan, Judith Hellman, Mark Schumacher
Format: Article
Language:English
Published: F1000 Research Ltd 2016-09-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-2425/v1