The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review
Children with congenital heart disease have poorer oral health compared with healthy children. Oral diseases, such as dental caries and gingivitis, are associated with the oral microbiome. The objective of this review was to find evidence of differences in the bacterial colonization of the oral cavi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/12/10/1269 |
| _version_ | 1797572605545283584 |
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| author | Maria Hofmann Nelly Schulz-Weidner Norbert Krämer Torsten Hain |
| author_facet | Maria Hofmann Nelly Schulz-Weidner Norbert Krämer Torsten Hain |
| author_sort | Maria Hofmann |
| collection | DOAJ |
| description | Children with congenital heart disease have poorer oral health compared with healthy children. Oral diseases, such as dental caries and gingivitis, are associated with the oral microbiome. The objective of this review was to find evidence of differences in the bacterial colonization of the oral cavity of children with congenital heart disease (CHD) versus healthy children. A literature review was conducted according to predetermined criteria, including the need for controlled clinical trials. Half of the 14 studies that met the inclusion criteria reported significant differences in bacterial colonization in children with congenital heart disease. A variety of influencing factors were discussed. There is some evidence for alterations in the oral microflora as a result of physiopathological and treatment-related factors in children with CHD, but additional research is required to validate these findings. |
| first_indexed | 2024-03-10T20:58:19Z |
| format | Article |
| id | doaj.art-06cbc344fa604a44b8e8bfda6fdcab9b |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T20:58:19Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-06cbc344fa604a44b8e8bfda6fdcab9b2023-11-19T17:40:55ZengMDPI AGPathogens2076-08172023-10-011210126910.3390/pathogens12101269The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive ReviewMaria Hofmann0Nelly Schulz-Weidner1Norbert Krämer2Torsten Hain3Dental Clinic—Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, GermanyDental Clinic—Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, GermanyDental Clinic—Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, GermanyInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, GermanyChildren with congenital heart disease have poorer oral health compared with healthy children. Oral diseases, such as dental caries and gingivitis, are associated with the oral microbiome. The objective of this review was to find evidence of differences in the bacterial colonization of the oral cavity of children with congenital heart disease (CHD) versus healthy children. A literature review was conducted according to predetermined criteria, including the need for controlled clinical trials. Half of the 14 studies that met the inclusion criteria reported significant differences in bacterial colonization in children with congenital heart disease. A variety of influencing factors were discussed. There is some evidence for alterations in the oral microflora as a result of physiopathological and treatment-related factors in children with CHD, but additional research is required to validate these findings.https://www.mdpi.com/2076-0817/12/10/1269oral microbiomechildrencongenital heart disease |
| spellingShingle | Maria Hofmann Nelly Schulz-Weidner Norbert Krämer Torsten Hain The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review Pathogens oral microbiome children congenital heart disease |
| title | The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review |
| title_full | The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review |
| title_fullStr | The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review |
| title_full_unstemmed | The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review |
| title_short | The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review |
| title_sort | bacterial oral microbiome in children with congenital heart disease an extensive review |
| topic | oral microbiome children congenital heart disease |
| url | https://www.mdpi.com/2076-0817/12/10/1269 |
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