Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho.

INTRODUCTION: Current guidelines contraindicate TDF use when creatinine clearance (CrCl) falls below 50 ml/min. We report prevalence of abnormal renal function at baseline and factors associated with abnormal renal function from a community cohort in Lesotho. METHODS: We calculated changes in CrCl f...

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Bibliographic Details
Main Authors: Helen Bygrave, Katharina Kranzer, Katherine Hilderbrand, Guillaume Jouquet, Eric Goemaere, Nathalie Vlahakis, Laura Triviño, Lipontso Makakole, Nathan Ford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3047584?pdf=render