Tissue-specific increases in 11beta-hydroxysteroid dehydrogenase type 1 in normal weight postmenopausal women.

With age and menopause there is a shift in adipose distribution from gluteo-femoral to abdominal depots in women. Associated with this redistribution of fat are increased risks of type 2 diabetes and cardiovascular disease. Glucocorticoids influence body composition, and 11beta-hydroxysteroid dehydr...

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Bibliographic Details
Main Authors: Therése Andersson, Kotryna Simonyte, Ruth Andrew, Magnus Strand, Jonas Burén, Brian R Walker, Cecilia Mattsson, Tommy Olsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2795198?pdf=render