DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.

DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.

In embryonic stem cells (ESCs), the expression of development-related genes, including germ cell-related genes, is globally repressed. The transcription factor MAX represses germ cell-related gene expression in ESCs via PCGF6-polycomb repressive complex 1 (PRC1), which consists of several epigenetic...

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Bibliographic Details
Main Authors: Daiki Tatsumi, Yohei Hayashi, Mai Endo, Hisato Kobayashi, Takumi Yoshioka, Kohei Kiso, Shinichiro Kanno, Yuji Nakai, Ikuma Maeda, Kentaro Mochizuki, Makoto Tachibana, Haruhiko Koseki, Akihiko Okuda, Akira Yasui, Tomohiro Kono, Yasuhisa Matsui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6221296?pdf=render

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http://europepmc.org/articles/PMC6221296?pdf=render

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