Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma

Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma

We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS2000) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC12) for the treatment of glioblastoma. The DOXC12-TOS-TPGS20...

Full description

Bibliographic Details
Main Authors: Mingchao Wang, Alessio Malfanti, Chiara Bastiancich, Véronique Préat
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Glioblastoma
Micelles
α-Tocopherol succinate
Doxorubicin
Drug delivery
Combination therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S259015672200038X

Internet

http://www.sciencedirect.com/science/article/pii/S259015672200038X

Similar Items