Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation

Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturation

G protein‐activated inward‐rectifying potassium (K+) channels (Kir3/GIRK) participate in cell excitability. The GIRK5 channel is present in Xenopus laevis oocytes. In an attempt to investigate the physiological role of GIRK5, we identified a noncanonical di‐arginine endoplasmic reticulum (ER) retent...

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Bibliographic Details
Main Authors: Claudia I. Rangel‐Garcia, Carolina Salvador, Karla Chavez‐Garcia, Beatriz Diaz‐Bello, Zinaeli Lopez‐Gonzalez, Lourdes Vazquez‐Cruz, Julio Angel Vazquez‐Martinez, Vianney Ortiz‐Navarrete, Hector Riveros‐Rosas, Laura I. Escobar
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:FEBS Open Bio
Subjects:
endoplasmic retention motif
G protein‐activated potassium channel
nested genes
oocyte
Xenopus
Online Access:https://doi.org/10.1002/2211-5463.13113

Internet

https://doi.org/10.1002/2211-5463.13113

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