P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment

The P2X7 receptor is an ATP-gated cation channel with a still ambiguous role in cancer progression, proposed to be either pro- or anti-cancerous, depending on the cancer or cell type in the tumour. Its role in mammary cancer progression is not yet defined. Here, we show that P2X7 receptor is functio...

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Bibliographic Details
Main Authors: Lucie Brisson, Stéphanie Chadet, Osbaldo Lopez-Charcas, Bilel Jelassi, David Ternant, Julie Chamouton, Stéphanie Lerondel, Alain Le Pape, Isabelle Couillin, Aurélie Gombault, Fabrice Trovero, Stéphan Chevalier, Pierre Besson, Lin-Hua Jiang, Sébastien Roger
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
P2X7 receptor
cancer cell invasiveness
invadopodia
metastases
antagonists
Online Access:https://www.mdpi.com/2072-6694/12/9/2342

Internet

https://www.mdpi.com/2072-6694/12/9/2342

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