Relationship between Epithelial-to-Mesenchymal Transition and Tumor-Associated Macrophages in Colorectal Liver Metastases

Relationship between Epithelial-to-Mesenchymal Transition and Tumor-Associated Macrophages in Colorectal Liver Metastases

The liver is the most common metastatic site in colorectal cancer (CRC) patients. Indeed, 25–30% of the cases develop colorectal liver metastasis (CLM), showing an extremely poor 5-year survival rate and resistance to conventional anticancer therapies. Tumor-associated macrophages (TAMs) provide a n...

Full description

Bibliographic Details
Main Authors: Aurora Gazzillo, Michela Anna Polidoro, Cristiana Soldani, Barbara Franceschini, Ana Lleo, Matteo Donadon
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal liver metastases
epithelial-to-mesenchymal transition
tumor-associated macrophages
TGF-β signaling
Online Access:https://www.mdpi.com/1422-0067/23/24/16197

Internet

https://www.mdpi.com/1422-0067/23/24/16197

Similar Items