An evidence-based and risk-adapted GSF versus GSF plus plerixafor mobilization strategy to obtain a sufficient CD34+ cell yield in the harvest for autologous stem cell transplants

An evidence-based and risk-adapted GSF versus GSF plus plerixafor mobilization strategy to obtain a sufficient CD34+ cell yield in the harvest for autologous stem cell transplants

Background: Plerixafor is a bicyclam molecule with the ability to reversibly bind to receptor CXCR-4 thus leading to an increased release of stem cells (SC) into the circulation. This study aims to evaluate the efficacy of G-CSF plus plerixafor versus G-CSF alone mobilizing regimens on the basis of...

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Bibliographic Details
Main Authors: Milena Todorović Balint, Nikola Lemajić, Vladimir Jurišić, Sofija Pantelić, Dejana Stanisavljević, Nada Kraguljac Kurtović, Bela Balint
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Translational Oncology
Subjects:
CD34+ cell mobilization
Cytokines
G-CSF
Plerixafor
Autologous transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323001973

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http://www.sciencedirect.com/science/article/pii/S1936523323001973

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