Context-dependent effects of the CB1 receptor antagonist rimonabant on morphine-induced behavioral sensitization in female mice

Context-dependent effects of the CB1 receptor antagonist rimonabant on morphine-induced behavioral sensitization in female mice

Introduction: The endocannabinoid system has been implicated in the neurobiology of opioid use disorder. While the CB1 receptor antagonist rimonabant has been shown to block some of the behavioral effects of opioids, studies suggest that the treatment environment (i.e., receiving treatment in the dr...

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Bibliographic Details
Main Authors: Eduardo A. V. Marinho, Alexandre Justo Oliveira-Lima, Henrique S. Reis, Renan Santos-Baldaia, Raphael Wuo-Silva, Andre W. Hollais, Thais S. Yokoyama, Roberto Frussa-Filho, Lais F. Berro
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
morphine
rimonabant
CB1 receptor
environment
context
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1100527/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1100527/full

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