Transcriptomic profiling across human serotonin neuron differentiation via the FEV reporter system

Transcriptomic profiling across human serotonin neuron differentiation via the FEV reporter system

Abstract Background The detailed transcriptomic profiles during human serotonin neuron (SN) differentiation remain elusive. The establishment of a reporter system based on SN terminal selector holds promise to produce highly-purified cells with an early serotonergic fate and help elucidate the molec...

Full description

Bibliographic Details
Main Authors: Yingqi Li, Jinjin Duan, You Li, Meihui Zhang, Jiaan Wu, Guanhao Wang, Shuanqing Li, Zhangsen Hu, Yi Qu, Yunhe Li, Xiran Hu, Fei Guo, Lining Cao, Jianfeng Lu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Stem Cell Research & Therapy
Subjects:
Serotonin neurons
FEV-EGFP reporter
Human pluripotent stem cells
Differentiation
CRISPR/Cas9
Online Access:https://doi.org/10.1186/s13287-024-03728-x

Internet

https://doi.org/10.1186/s13287-024-03728-x

Similar Items