Extent of hematopoietic involvement by TET2 mutations in JAK2V617F polycythemia vera

TET2 mutations are found in polycythemia vera and it was initially reported that there is a greater TET2 mutational burden than JAK2V617F in polycythemia vera stem cells and that TET2 mutations precede JAK2V617F. We quantified the proportion of TET2, JAK2V617F mutations and X-chromosome allelic usag...

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Bibliographic Details
Main Authors: Sabina I. Swierczek, Donghoon Yoon, Christine Bellanné-Chantelot, Soo Jin Kim, Cécile Saint-Martin, Francois Delhommeau, Albert Najman, Josef T. Prchal
Format: Article
Language:English
Published: Ferrata Storti Foundation 2011-05-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5976