Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment

Abstract Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing performance. In this study, we introduce a novel droplet microfluidic chip to overcome this challenge. The chip comprises a double spiral focusing uni...

Full description

Bibliographic Details
Main Authors: Tao Tang, Hao Zhao, Shaofei Shen, Like Yang, Chwee Teck Lim
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-023-00631-y