Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells

Elevated expression of the RNA-binding protein IGF2BP1 enhances the mRNA stability of INHBA to promote the invasion and migration of esophageal squamous cancer cells

Abstract Background The mechanisms underlying the occurrence and development of esophageal squamous cell carcinoma (ESCC) remains to be elucidated. The present study aims to investigate the roles and implications of IGF2BP1 overexpression in ESCC. Methods IGF2BP1 protein expression in ESCC samples w...

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Bibliographic Details
Main Authors: Juan-Juan Wang, Ding-Xiong Chen, Yu Zhang, Xin Xu, Yan Cai, Wen-Qiang Wei, Jia-Jie Hao, Ming-Rong Wang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Experimental Hematology & Oncology
Subjects:
Esophageal squamous cell carcinoma
Migration
Invasion
RNA binding protein
IGF2BP1
INHBA
Online Access:https://doi.org/10.1186/s40164-023-00429-8

Internet

https://doi.org/10.1186/s40164-023-00429-8

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