Enalapril Diminishes the Diabetes-Induced Changes in Intestinal Morphology, Intestinal RAS and Blood SCFA Concentration in Rats

Enalapril Diminishes the Diabetes-Induced Changes in Intestinal Morphology, Intestinal RAS and Blood SCFA Concentration in Rats

Evidence suggests that microbiota-derived metabolites, including short-chain fatty acids (SCFAs) and trimethylamine-oxide (TMAO), affect the course of diabetic multiorgan pathology. We hypothesized that diabetes activates the intestinal renin–angiotensin system (RAS), contributing to gut pathology....

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Bibliographic Details
Main Authors: Kinga Jaworska, Wojciech Kopacz, Mateusz Koper, Mateusz Szudzik, Marta Gawryś-Kopczyńska, Marek Konop, Tomasz Hutsch, Dawid Chabowski, Marcin Ufnal
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
intestinal RAS
diabetes
ACE-I
SCFA
TMAO
Online Access:https://www.mdpi.com/1422-0067/23/11/6060

Internet

https://www.mdpi.com/1422-0067/23/11/6060

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