Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally

Nanoparticles (NPs) are increasingly being used for drug delivery, as well as antigen carriers and immunostimulants for the purpose of developing vaccines. In this work, we examined how intranasal (i.n.) priming followed by i.n. or subcutaneous (s.c.) boosting immunization affects the humoral immune...

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Bibliographic Details
Main Authors: Savannah E. Howe, Gavin Sowa, Vjollca Konjufca
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Antibodies
Subjects:
Online Access:http://www.mdpi.com/2073-4468/5/4/20