6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Alleviates Oxidative Stress and NF-κB-Mediated Inflammation in Rats with Experimental Parkinson’s Disease

6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Alleviates Oxidative Stress and NF-κB-Mediated Inflammation in Rats with Experimental Parkinson’s Disease

A study was conducted to investigate the effects of different doses of 6-hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline (HTHQ) on motor coordination scores, brain tissue morphology, the expression of tyrosine hydroxylase, the severity of oxidative stress parameters, the levels of the p65 subuni...

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Bibliographic Details
Main Authors: Evgenii D. Kryl’skii, Grigorii A. Razuvaev, Tatyana N. Popova, Svetlana M. Medvedeva, Khidmet S. Shikhaliev
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Current Issues in Molecular Biology
Subjects:
Parkinson’s disease
quinoline derivatives
6-hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline
oxidative stress
inflammation
nuclear factor kappa-light-chain-enhancer of activated B cells
Online Access:https://www.mdpi.com/1467-3045/45/9/483

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https://www.mdpi.com/1467-3045/45/9/483

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