Co-Overexpression of TWIST1-CSF1 Is a Common Event in Metastatic Oral Cancer and Drives Biologically Aggressive Phenotype

Co-Overexpression of TWIST1-CSF1 Is a Common Event in Metastatic Oral Cancer and Drives Biologically Aggressive Phenotype

Invasive oral squamous cell carcinoma (OSCC) is often ulcerated and heavily infiltrated by pro-inflammatory cells. We conducted a genome-wide profiling of tissues from OSCC patients (early versus advanced stages) with 10 years follow-up. Co-amplification and co-overexpression of <i>TWIST1</...

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Bibliographic Details
Main Authors: Sabrina Daniela da Silva, Fabio Albuquerque Marchi, Jie Su, Long Yang, Ludmila Valverde, Jessica Hier, Krikor Bijian, Michael Hier, Alex Mlynarek, Luiz Paulo Kowalski, Moulay A. Alaoui-Jamali
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
oral squamous cell carcinoma
tumor invasion
metastasis
genomic
tumor-associated macrophages
EMT
Online Access:https://www.mdpi.com/2072-6694/13/1/153

Internet

https://www.mdpi.com/2072-6694/13/1/153

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