High-resolution confocal and light-sheet imaging of collagen 3D network architecture in very large samples

Summary: Although notoriously difficult, imaging collagen network architecture, a key element affecting tissue mechanical properties, is of paramount importance in developmental and cancer biology. Here, we introduce a simple and robust method of whole-mount collagen staining with the ‘Fast Green’ d...

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Bibliographic Details
Main Authors: Grigorii Timin, Michel C. Milinkovitch
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223005291