Aspirin prevents estrogen deficiency-induced bone loss by inhibiting osteoclastogenesis and promoting osteogenesis

Aspirin prevents estrogen deficiency-induced bone loss by inhibiting osteoclastogenesis and promoting osteogenesis

Abstract Background Aspirin is a commonly used antipyretic, analgesic, and anti-inflammatory drug. Numerous researches have demonstrated that aspirin exerts multiple biological effects on bone metabolism. However, its spatiotemporal roles remain controversial according to the specific therapeutic do...

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Bibliographic Details
Main Authors: Yongyun Chang, Keyu Kong, Zhicheng Tong, Hua Qiao, Yi Hu, Runzhi Xia, Jingwei Zhang, Zanjing Zhai, Huiwu Li
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Aspirin
Osteoclastogenesis
Osteogenesis
Osteoporosis
NF-κB
MAPK
Online Access:https://doi.org/10.1186/s13018-023-03710-y

Internet

https://doi.org/10.1186/s13018-023-03710-y

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