Dual protective role of velutin against articular cartilage degeneration and subchondral bone loss via the p38 signaling pathway in murine osteoarthritis

Dual protective role of velutin against articular cartilage degeneration and subchondral bone loss via the p38 signaling pathway in murine osteoarthritis

Osteoarthritis (OA) is a common degenerative joint condition associated with inflammation and characterized by progressive degradation of the articular cartilage and subchondral bone loss in the early stages. Inflammation is closely associated with these two major pathophysiological changes in OA. V...

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Bibliographic Details
Main Authors: Kelei Wang, Xuanyuan Lu, Xinyu Li, Yufeng Zhang, Rongjian Xu, Yun Lou, Yanben Wang, Tan Zhang, Yu Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Endocrinology
Subjects:
velutin
chondrocyte
subchondral bone
p38 pathway
osteoarthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.926934/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.926934/full

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