Hypoxia endothelial cells-derived exosomes facilitate diabetic wound healing through improving endothelial cell function and promoting M2 macrophages polarization

Hypoxia endothelial cells-derived exosomes facilitate diabetic wound healing through improving endothelial cell function and promoting M2 macrophages polarization

It is imperative to develop and implement newer, more effective strategies to address refractory diabetic wounds. As of now, there is currently no optimal solution for these wounds. Hypoxic human umbilical vein endothelial cells (HUVECs)-derived exosomes have been postulated to promote diabetic woun...

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Bibliographic Details
Main Authors: Peng Cheng, Xudong Xie, Liangcong Hu, Wu Zhou, Bobin Mi, Yuan Xiong, Hang Xue, Kunyu Zhang, Yuxiao Zhang, Yiqiang Hu, Lang Chen, Kangkang Zha, Bin Lv, Ze Lin, Chuanlu Lin, Guandong Dai, Yixin Hu, Tengbo Yu, Hankun Hu, Guohui Liu, Yingze Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Bioactive Materials
Subjects:
Diabetic wound
Hypoxic exosomes
lncHAR1B
KLF4
Macrophage polarization
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003353

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X23003353

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