Continuous Versus Intermittent Linezolid Infusion for Critically Ill Patients with Hospital-Acquired and Ventilator-Associated Pneumonia: Efficacy and Safety Challenges

Continuous Versus Intermittent Linezolid Infusion for Critically Ill Patients with Hospital-Acquired and Ventilator-Associated Pneumonia: Efficacy and Safety Challenges

High variability of linezolid blood concentrations with partial subtherapeutic levels was observed in critically ill patients who received a standard intravenous dose of linezolid, contributing to drug resistance and toxicity. Continuous infusions of linezolid have been suggested as an alternative a...

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Bibliographic Details
Main Authors: Ahmed E. Abou Warda, Rania M. Sarhan, Hussein Saeed Al-Fishawy, Ayman N. Moharram, Heba F. Salem
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceuticals
Subjects:
linezolid
intensive care unit
continuous infusion
intermittent infusion
clinical response
thrombocytopenia
Online Access:https://www.mdpi.com/1424-8247/15/3/296

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https://www.mdpi.com/1424-8247/15/3/296

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