Triphenylphosphonium Analogs of Short Peptide Related to Bactenecin 7 and Oncocin 112 as Antimicrobial Agents

Triphenylphosphonium Analogs of Short Peptide Related to Bactenecin 7 and Oncocin 112 as Antimicrobial Agents

Antimicrobial peptides (AMPs) have recently attracted attention as promising antibacterial agents capable of acting against resistant bacterial strains. In this work, an approach was applied, consisting of the conjugation of a peptide related to the sequences of bactenecin 7 (Bac7) and oncocin (Onc1...

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Main Authors: Andrey G. Tereshchenkov, Zimfira Z. Khairullina, Inna A. Volynkina, Dmitrii A. Lukianov, Pavel A. Nazarov, Julia A. Pavlova, Vadim N. Tashlitsky, Elizaveta A. Razumova, Daria A. Ipatova, Yury V. Timchenko, Dmitry A. Senko, Olga V. Efremenkova, Alena Paleskava, Andrey L. Konevega, Ilya A. Osterman, Igor A. Rodin, Petr V. Sergiev, Olga A. Dontsova, Alexey A. Bogdanov, Natalia V. Sumbatyan
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceutics
Subjects:
alkyl(triphenyl)phosphonium
proline–arginine-rich antimicrobial peptides
bactenecin 7
oncocin 112
bacterial ribosome
bacterial membrane potential
Online Access:https://www.mdpi.com/1999-4923/16/1/148

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https://www.mdpi.com/1999-4923/16/1/148

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