Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus with no specific treatment or vaccine available. Here, the authors develop a DNA vaccine for SFTSV that is protective against lethal challenge in ferrets and show that anti-envelope antibodies are important for...

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Bibliographic Details
Main Authors: Jeong-Eun Kwak, Young-Il Kim, Su-Jin Park, Min-Ah Yu, Hyeok-Il Kwon, Sukyeong Eo, Tae-Shin Kim, Joon Seok, Won-Suk Choi, Ju Hwan Jeong, Hyojin Lee, Youngran Cho, Jin Ah Kwon, Moonsup Jeong, Joel N. Maslow, Yong-Eun Kim, Haili Jeon, Kee K. Kim, Eui-Cheol Shin, Min-Suk Song, Jae U. Jung, Young Ki Choi, Su-Hyung Park
Format: Article
Language:English
Published: Nature Portfolio 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11815-4

Internet

https://doi.org/10.1038/s41467-019-11815-4

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