GM-CSF/IL-3/IL-5 receptor common β chain (CD131) expression as a biomarker of antigen-stimulated CD8<sup>+ </sup>T cells

GM-CSF/IL-3/IL-5 receptor common β chain (CD131) expression as a biomarker of antigen-stimulated CD8<sup>+ </sup>T cells

<p>Abstract</p> <p>Background</p> <p>Upon Ag-activation cytotoxic T cells (CTLs) produce IFN-γ GM-CSF and TNF-α, which deliver simultaneously pro-apoptotic and pro-inflammatory signals to the surrounding microenvironment. Whether this secretion affects in an autocrine l...

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Bibliographic Details
Main Authors: Maric Dragan, Panelli Monica C, Rumio Cristiano, Slezak Stefanie L, Worschech Andrea, Jin Ping, Pos Zoltan, Deola Sara, Selleri Silvia, Stroncek David F, Wang Ena, Marincola Francesco M
Format: Article
Language:English
Published: BMC 2008-04-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/17

Internet

http://www.translational-medicine.com/content/6/1/17

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