Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice
Abstract Background Transplantation of human hematopoietic stem cells into immunodeficient mice provides a powerful in vivo model system to gain functional insights into hematopoietic differentiation. So far, it remains unclear if epigenetic changes of normal human hematopoiesis are recapitulated up...
| Главные авторы: | , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
BMC
2018-05-01
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| Серии: | Clinical Epigenetics |
| Предметы: | |
| Online-ссылка: | http://link.springer.com/article/10.1186/s13148-018-0499-7 |