Individual differences in the effects of midazolam on anxiety-like behavior, learning, reward, and choice behavior in male mice

Individual differences in the effects of midazolam on anxiety-like behavior, learning, reward, and choice behavior in male mice

IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were submitted to the training session of a discriminati...

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Main Authors: Caio Jovita-Farias, Meagan E. Follett, Behaim C. Dias-Junior, Yasmim A. Serra, Natali D. Kisaki, Thaísa Barros-Santos, Nailton M. S. de Jesus, Isa R. S. Rodrigues, Larissa E. L. Macedo, Elena L. A. Malpezzi-Marinho, Alexandre J. Oliveira-Lima, Eduardo Ary Villela Marinho, James K. Rowlett, Lais F. Berro
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Psychiatry
Subjects:
benzodiazepine
midazolam
elevated plus maze
self-administration
conditioned place preference
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1122568/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1122568/full

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