A comparative analysis of RNA sequencing methods with ribosome RNA depletion for degraded and low-input total RNA from formalin-fixed and paraffin-embedded samples

A comparative analysis of RNA sequencing methods with ribosome RNA depletion for degraded and low-input total RNA from formalin-fixed and paraffin-embedded samples

Abstract Background Formalin-fixed and paraffin-embedded (FFPE) blocks held in clinical laboratories are an invaluable resource for clinical research, especially in the era of personalized medicine. It is important to accurately quantitate gene expression with degraded and small amounts of total RNA...

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Bibliographic Details
Main Authors: Xiaojing Lin, Lihong Qiu, Xue Song, Junyan Hou, Weizhi Chen, Jun Zhao
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Genomics
Subjects:
RNA-seq
rRNA depletion
HISAT
Degraded FFPE sample
Online Access:http://link.springer.com/article/10.1186/s12864-019-6166-3

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http://link.springer.com/article/10.1186/s12864-019-6166-3

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