Broad-spectrum and powerful neutralization of bacterial toxins by erythroliposomes with the help of macrophage uptake and degradation

Broad-spectrum and powerful neutralization of bacterial toxins by erythroliposomes with the help of macrophage uptake and degradation

Anti-virulence strategy has been considered as one of the most promising approaches to combat drug-resistant bacterial infections. Pore-forming toxins (PFTs) are the largest class of bacterial toxins, inflicting their virulence effect through creating pores on the cell membrane. However, current sol...

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Bibliographic Details
Main Authors: Chunying Liu, Shuangrong Ruan, Ying He, Xuejing Li, Yuefei Zhu, Honglan Wang, Hanwei Huang, Zhiqing Pang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Erythroliposome
Broad-spectrum detoxification
Hybrid nanovesicle
Pore-forming toxins
Macrophage uptake
Red blood cell membrane
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522001459

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http://www.sciencedirect.com/science/article/pii/S2211383522001459

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