Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice

Abstract Reduced reward interest/learning and reward-to-effort valuation are distinct, common symptoms in neuropsychiatric disorders for which chronic stress is a major aetiological factor. Glutamate neurons in basal amygdala (BA) project to various regions including nucleus accumbens (NAc). The BA-...

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Bibliographic Details
Main Authors: Lorraine Madur, Christian Ineichen, Giorgio Bergamini, Alexandra Greter, Giulia Poggi, Nagiua Cuomo-Haymour, Hannes Sigrist, Yaroslav Sych, Jean-Charles Paterna, Klaus D. Bornemann, Coralie Viollet, Francesc Fernandez-Albert, Gregorio Alanis-Lobato, Bastian Hengerer, Christopher R. Pryce
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04811-4