Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

ABSTRACT Integrons ensure a rapid and “on demand” response to environmental stresses driving bacterial adaptation. They are able to capture, store, and reorder functional gene cassettes due to site-specific recombination catalyzed by their integrase. Integrons can be either sedentary and chromosomal...

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Bibliographic Details
Main Authors: Céline Loot, Aleksandra Nivina, Jean Cury, José Antonio Escudero, Magaly Ducos-Galand, David Bikard, Eduardo P. C. Rocha, Didier Mazel
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Subjects:
integron
attC sites
cassette dynamics
replication
site-specific recombination
Online Access:https://journals.asm.org/doi/10.1128/mBio.02296-16

Internet

https://journals.asm.org/doi/10.1128/mBio.02296-16

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