Role of tannic acid against SARS-cov-2 cell entry by targeting the interface region between S-protein-RBD and human ACE2

Role of tannic acid against SARS-cov-2 cell entry by targeting the interface region between S-protein-RBD and human ACE2

Coronavirus disease 2019 (COVID-19) was caused by a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 utilizes human angiotensin converting enzyme 2 (hACE2) as the cellular receptor of its spike glycoprotein (SP) to gain entry into cells. Consequently, we focu...

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Bibliographic Details
Main Authors: Xi Chen, Ziyuan Wang, Jing Wang, Yifan Yao, Qian Wang, Jiahao Huang, Xianping Xiang, Yifan Zhou, Yintong Xue, Yan Li, Xiang Gao, Lijun Wang, Ming Chu, Yuedan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
COVID-19
SARS-cov-2
spike protein
SARS-cov-2-RBD
hACE2
tannic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.940628/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.940628/full

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