A Biterm Topic Model for Sparse Mutation Data

Mutational signature analysis promises to reveal the processes that shape cancer genomes for applications in diagnosis and therapy. However, most current methods are geared toward rich mutation data that has been extracted from whole-genome or whole-exome sequencing. Methods that process sparse muta...

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Bibliographic Details
Main Authors: Itay Sason, Yuexi Chen, Mark D. M. Leiserson, Roded Sharan
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/5/1601