In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410.

The aim of this study was to investigate the physicochemical and in vitro/ex vivo characteristics of the pyrmidinedione IQP-0410 formulated into transdermal films. IQP-0410 is a potent therapeutic anti-HIV nonnucleoside reverse transcriptase inhibitor that would be subjected to extensive first pass...

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Bibliographic Details
Main Authors: Anthony S Ham, William Lustig, Lu Yang, Ashlee Boczar, Karen W Buckheit, Robert W Buckheit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776786?pdf=render