Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome

Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome

Summary: Altered neural dynamics in the medial prefrontal cortex (mPFC) and hippocampus may contribute to cognitive impairments in the complex chromosomal disorder Down syndrome (DS). Here, we demonstrate non-overlapping behavioral differences associated with distinct abnormalities in hippocampal an...

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Bibliographic Details
Main Authors: Pishan Chang, Daniel Bush, Stephanie Schorge, Mark Good, Tara Canonica, Nathanael Shing, Suzanna Noy, Frances K. Wiseman, Neil Burgess, Victor L.J. Tybulewicz, Matthew C. Walker, Elizabeth M.C. Fisher
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471931722X

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http://www.sciencedirect.com/science/article/pii/S221112471931722X

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