Effects of cisplatin on lipid peroxidation and the glutathione redox status in the liver of male rats: The protective role of selenium

Effects of cisplatin on lipid peroxidation and the glutathione redox status in the liver of male rats: The protective role of selenium

The role of oxidative stress in cisplatin (CP) toxicity and its prevention by pretreatment with selenium (Se) was investigated. Male Wistar albino rats were injected with a single dose of cisplatin (7.5 mg CP/kg b.m., i.p.) and selenium (6 mg Se/kg b.m, as Na2SeO3, i.p.) alone or in combination. The...

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Bibliographic Details
Main Authors: Trbojević Ivana S., Ognjanović Branka I., Đorđević Nataša Z., Marković Snežana D., Štajn A.Š., Gavrić Jelena P., Saičić Zorica S.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2010-01-01
Series:Archives of Biological Sciences
Subjects:
Cisplatin
selenium
lipid peroxidation
glutathione redox status
liver
rat
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641001075T.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641001075T.pdf

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