New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors

New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors

The permeability of large cations through the P2X pore has remained arguably the most controversial and complicated topic in P2X-related research, with the emergence of conflicting studies on the existence, mechanism and physiological relevance of a so-called “dilated” state. Due to the important ro...

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Bibliographic Details
Main Authors: Laurie Peverini, Juline Beudez, Kate Dunning, Thierry Chataigneau, Thomas Grutter
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
LGICs
P2X receptors
dilation
spermidine
ion permeation
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00265/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00265/full

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