Comparative analysis of potential broad-spectrum neuronal Cre drivers [version 1; peer review: 2 approved]

Cre/Lox technology is a powerful tool in the mouse genetics tool-box as it enables tissue-specific and inducible mutagenesis of specific gene loci. Correct interpretation of phenotypes depends upon knowledge of the Cre expression pattern in the chosen mouse driver line to ensure that appropriate cel...

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Bibliographic Details
Main Authors: Jim Selfridge, Katie M Paton, Adrian Bird, Jacky Guy
Format: Article
Language:English
Published: Wellcome 2022-07-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/7-185/v1