Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein.

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein.

The Fanconi Anemia (FA) pathway is important for repairing interstrand crosslinks (ICLs) between the Watson-Crick strands of the DNA double helix. An initial and essential stage in the repair process is the detection of the ICL. Here, we report the identification of UHRF2, a paralogue of UHRF1, as a...

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Bibliographic Details
Main Authors: Anna Motnenko, Chih-Chao Liang, Di Yang, David Lopez-Martinez, Yasunaga Yoshikawa, Bao Zhan, Katherine E Ward, Jiayang Tian, Wilhelm Haas, Paolo Spingardi, Benedikt M Kessler, Skirmantas Kriaucionis, Steven P Gygi, Martin A Cohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6193622?pdf=render

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http://europepmc.org/articles/PMC6193622?pdf=render

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