The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

The hypoxia-driven crosstalk between tumor and tumor-associated macrophages: mechanisms and clinical treatment strategies

Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently. Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironme...

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Bibliographic Details
Main Authors: Ruixue Bai, Yunong Li, Lingyan Jian, Yuehui Yang, Lin Zhao, Minjie Wei
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Molecular Cancer
Subjects:
Hypoxia-inducible factor
Oxygen sensor
Intercellular communication
Inhibitor
Online Access:https://doi.org/10.1186/s12943-022-01645-2

Internet

https://doi.org/10.1186/s12943-022-01645-2

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