Neuroprotective effects of Danshensu on rotenone-induced Parkinson’s disease models in vitro and in vivo

Abstract Background Danshensu is an active constituent in the extracts of Danshen which is a traditional Chinese medical herb. Rotenone inhibits complex I of the mitochondrial electron transport chain in dopaminergic neurons leading to glutathione (GSH) level reduction and oxidative stress. The aim...

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Bibliographic Details
Main Authors: Tian Wang, Cuiting Li, Bing Han, Zhenhua Wang, Xiaoyu Meng, Leiming Zhang, Jie He, Fenghua Fu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-019-2738-7