The Intron 4 Polymorphism in the Calcium-Sensing Receptor Gene in Diabetes Mellitus and its Chronic Complications, Diabetic Nephropathy and Non-Diabetic Renal Disease

Background/Aims: Calcium-Sensing Receptor (CaSR) significantly affects calcium-phosphate metabolism in kidneys, and it is implicated in the pathogenesis of diabetes mellitus (DM) due to its expression in pancreatic F-cells. The role of CaSR as one of the players in pathogenesis of chronic kidney dis...

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Bibliographic Details
Main Authors: Viera Železníková, Marcela Vedralová, Anna Kotrbová-Kozak, Hana Zoubková, Marie Černá, Ivan Rychlík
Format: Article
Language:English
Published: Karger Publishers 2014-10-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/368453