Whole genome sequencing of mutation accumulation lines reveals a low mutation rate in the social amoeba Dictyostelium discoideum.

Spontaneous mutations play a central role in evolution. Despite their importance, mutation rates are some of the most elusive parameters to measure in evolutionary biology. The combination of mutation accumulation (MA) experiments and whole-genome sequencing now makes it possible to estimate mutatio...

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Bibliographic Details
Main Authors: Gerda Saxer, Paul Havlak, Sara A Fox, Michael A Quance, Sharu Gupta, Yuriy Fofanov, Joan E Strassmann, David C Queller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466296?pdf=render