The small trial problem

Abstract Background Many randomized trials that aim to assess new or commonly used medical or surgical interventions have been so small that the validity of conclusions becomes questionable. Methods We illustrate the small trial problem using the power calculation of five Cochrane-reviewed studies t...

Full description

Bibliographic Details
Main Authors: Jean Raymond, Tim E. Darsaut, Johanna Eneling, Miguel Chagnon
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07348-3