Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

Summary: Pre-clinical studies of fragile X syndrome (FXS) have focused on neurons, with the role of glia remaining largely underexplored. We examined the astrocytic regulation of aberrant firing of FXS neurons derived from human pluripotent stem cells. Human FXS cortical neurons, co-cultured with hu...

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Bibliographic Details
Main Authors: Shreya Das Sharma, Bharath Kumar Reddy, Rakhi Pal, Tuula E. Ritakari, James D. Cooper, Bhuvaneish T. Selvaraj, Peter C. Kind, Siddharthan Chandran, David J.A. Wyllie, Sumantra Chattarji
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003558

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http://www.sciencedirect.com/science/article/pii/S2211124723003558

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